The estimates of effective population size based on linkage disequilibrium are virtually unaffected by natural selection
Abstract The effective population size (Ne) is a key parameter to quantify the magnitude of genetic drift and inbreeding, with…
Polypolish: Short-read polishing of long-read bacterial genome assemblies
Abstract Long-read-only bacterial genome assemblies usually contain residual errors, most commonly homopolymer-length errors. Short-read polishing tools can use short reads…
Isolation, characterization and application of bacteriophage PSDA-2 against Salmonella Typhimurium in chilled mutton
Abstract Salmonella is a common foodborne pathogen, especially in meat and meat products. Lytic phages are promising alternatives to conventional…
Demography and selection analysis of the incipient adaptive radiation of a Hawaiian woody species
Citation: Izuno A, Onoda Y, Amada G, Kobayashi K, Mukai M, Isagi Y, et al. (2022) Demography and selection analysis…
Genome-wide association study of cassava starch paste properties
Citation: Santos CSd, Sousa MB, Brito AC, de Oliveira LA, Carvalho CWP, de Oliveira EJ (2022) Genome-wide association study of…
Detection and characterization of genome-wide mutations in M1 vegetative cells of gamma-irradiated Arabidopsis
Abstract Radiation-induced mutations have been detected by whole-genome sequencing analyses of self-pollinated generations of mutagenized plants. However, large DNA alterations…
RNA reference materials with defined viral RNA loads of SARS-CoV-2—A useful tool towards a better PCR assay harmonization
Abstract SARS-CoV-2, the cause of COVID-19, requires reliable diagnostic methods to track the circulation of this virus. Following the development…
Massively parallel reporter assays discover de novo exonic splicing mutants in paralogs of Autism genes
Abstract To determine the contribution of defective splicing in Autism Spectrum Disorders (ASD), the most common neurodevelopmental disorder, a high…
Genome-wide association study identifies genetic risk loci for adiposity in a Taiwanese population
Abstract Overweight and obese are risk factors for various diseases. In Taiwan, the combined prevalence of overweight and obesity has…
Genomic surveillance of SARS-CoV-2 in the state of Delaware reveals tremendous genomic diversity
Abstract The use of next generation sequencing is critical for the surveillance of severe acute respiratory syndrome coronavirus 2, SARS-CoV-2,…