Efficacy of rifaximin against covert hepatic encephalopathy and hyperammonemia in Japanese patients
Abstract Covert hepatic encephalopathy (CHE) impairs patient quality of life and occurs in approximately 30% of liver cirrhosis (LC) cases. Japanese clinical practice guidelines recommend rifaximin to treat overt HE…
Diagnostic of FibroTouch and six serological models in assessing the degree of liver fibrosis among patients with chronic hepatic disease: A single-center retrospective study
Abstract Background and aims The aim of this study was to evaluate the diagnostic value of FibroTouch and serological models on staging hepatic fibrosis in chronic liver diseases. Methods We…
Symptoms of depression, anxiety and stress in patients with chronic otitis media
Abstract Purpose Persistent symptoms of chronic otitis media cause limitations in daily routine and social interactions, influencing significantly patients’ quality of life and mental health. The purpose of the study…
Mixed methods prospective findings of the initial effects of the U.S. COVID-19 pandemic on individuals in recovery from substance use disorder
Abstract The beginning of the U.S. COVID-19 pandemic interrupted integral services and supports for those in recovery from substance use disorders. The current study used qualitative and quantitative data to…
Aspalathus linearis suppresses cell survival and proliferation of enzalutamide-resistant prostate cancer cells via inhibition of c-Myc and stability of androgen receptor
Abstract Enzalutamide, a nonsteroidal antiandrogen, significantly prolonged the survival of patients with metastatic castration-resistant prostate cancer (CRPC). However, patients receiving enzalutamide frequently develop drug resistance. Rooibos (Aspalathus linearis) is a…
Award rate inequities in biomedical research
Abstract Purpose The analysis of existing institutional research proposal databases can provide novel insights into science funding parity. The purpose of this study was to analyze the relationship between race/ethnicity…
Does knowing the influenza epidemic threshold has been reached influence the performance of influenza case definitions?
Abstract Background Disease surveillance using adequate case definitions is very important. The objective of the study was to compare the performance of influenza case definitions and influenza symptoms in the…
Sparse representation of brain signals offers effective computation of cortico-muscular coupling value to predict the task-related and non-task sEMG channels: A joint hdEEG-sEMG study
Abstract Cortico-muscular interactions play important role in sensorimotor control during motor task and are commonly studied by cortico-muscular coherence (CMC) method using joint electroencephalogram-surface electromyogram (EEG-sEMG) signals. As noise and…
Analysis of clinical trial registry entry histories using the novel R package cthist
## R Code Box 1 library(tidyverse) library(cthist) library(lubridate) ## To reproduce these methods, conduct a search on the ## ClinicalTrials.gov web front-end and download the result as a ## comma-separated…
Deep learning based lithology classification of drill core images
Abstract Drill core lithology is an important indicator reflecting the geological conditions of the drilling area. Traditional lithology identification usually relies on manual visual inspection, which is time-consuming and professionally…